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Oral Retinoids and Scaring after surgical procedures

6 to 12 months waiting period after isotretinoin treatment was the standard norms for  undergoing any kind surgical procedures like scar correction, dermabrasion, fractional resurfacing etc. 

Oral retinoids have been associated with suppression of collagenase, potentially causing excessive collagen accumulation and keloid formation, and possible atrophy of the pilosebaceous unit, where re-epithelialization for wound healing originates. 

But recent studies from medical record review, shown that wound healing did not appear to be affected, and abnormal scarring did not appear to be evident in patients undergoing isotretinoin therapy as compared with those not exposed to the medication in the perioperative period.